Glutathione S-transferase M1 polymorphism and the risk of lung cancer.

@article{Mohr2003GlutathioneSM,
  title={Glutathione S-transferase M1 polymorphism and the risk of lung cancer.},
  author={Lawrence C. Mohr and Jenna K Rodgers and Gerard A. Silvestri},
  journal={Anticancer research},
  year={2003},
  volume={23 3A},
  pages={2111-24}
}
Glutathione S-transferases (GSTs) are a family of enzymes that detoxify hydrophobic electrophiles, including polycyclic aromatic hydrocarbon carcinogens that have been implicated in the pathogenesis of lung cancer. The GSTM1 gene within the mu class of human GSTs has been shown to be polymorphic, with individuals who are homozygous for a null allele having… CONTINUE READING