Glutathione S-transferase M1 genotypes and the risk of squamous carcinoma of the cervix: a population-based case-control study.

@article{Chen1999GlutathioneSM,
  title={Glutathione S-transferase M1 genotypes and the risk of squamous carcinoma of the cervix: a population-based case-control study.},
  author={Chu Chen and M M Madeleine and Noel S Weiss and Janet R. Daling},
  journal={American journal of epidemiology},
  year={1999},
  volume={150 6},
  pages={568-72}
}
The authors determined the GSTM1 genotype of 190 Caucasian women with invasive squamous cell cervical cancer in western Washington State between January 1986 and June 1994 and of 206 controls. It was found that 53% of cases and 57% of controls had the GSTM1 null genotype. The age-adjusted odds ratio associated with GSTM1 null genotype was 0.8 (95% confidence interval 0.6, 1.3). The lack of association between cervical cancer risk and GSTM1 genotype was true both for smokers and nonsmokers of… CONTINUE READING