Glutathione S-transferase M1, T1 and P1 polymorphisms and bladder cancer risk in Egyptians.

@article{Saad2005GlutathioneSM,
  title={Glutathione S-transferase M1, T1 and P1 polymorphisms and bladder cancer risk in Egyptians.},
  author={Abir A. Saad and Patrick J. O'Connor and Mostafa Mostafa and Nabila E Metwalli and D. P. Cooper and Andrew C. Povey and G. P. Margison},
  journal={The International journal of biological markers},
  year={2005},
  volume={20 1},
  pages={69-72}
}
Previous studies suggest that bladder cancer risk may vary with GST genotype but these results are inconsistent. The aim of this study was to explore whether GSTM1, GSTT1 and GSTP polymorphisms were associated with increased bladder cancer risk in an Egyptian population. GSTM1, GSTT1 and GSTP1 genotype frequencies were determined in bladder cancer cases (n=72) and healthy controls with no history of malignancies (n=82) using PCR-based techniques. The GSTT1*2 genotype was particularly associated… CONTINUE READING
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