Glutathione Content of Colonic Mucosa (Evidence for Oxidative Damage in Active Ulcerative Colitis)

@article{Holmes1998GlutathioneCO,
  title={Glutathione Content of Colonic Mucosa (Evidence for Oxidative Damage in Active Ulcerative Colitis)},
  author={Edward W. Holmes and Sherri L. Yong and David Eiznhamer and Ali Keshavarzian},
  journal={Digestive Diseases and Sciences},
  year={1998},
  volume={43},
  pages={1088-1095}
}
Oxidative stress appears to play a role in thetissue damage of active ulcerative colitis, and it hasbeen suggested that a defect in mucosal antioxidantdefenses is a etiological factor in the disease. This study was undertaken to investigate themucosal content and oxidation state of glutathione inulcerative colitis in the active and inactive states andto examine the relationship between glutathione content and disease activity in this patientpopulation. Endoscopic biopsies of colon mucosa… CONTINUE READING