Glutathione: a vital lens antioxidant.

  title={Glutathione: a vital lens antioxidant.},
  author={Frank J. Giblin},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  volume={16 2},
  • Frank J. Giblin
  • Published 2000 in
    Journal of ocular pharmacology and therapeutics…
The reducing compound glutathione (GSH) exists in an unusually high concentration in the lens where it functions as an essential antioxidant vital for maintenance of the tissue's transparency. In conjunction with an active glutathione redox cycle located in the lens epithelium and superficial cortex, GSH detoxifies potentially damaging oxidants such as H2O2 and dehydroascorbic acid. Recent studies have indicated an important hydroxyl radical-scavenging function for GSH in lens epithelial cells… CONTINUE READING
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