Glutathione: a novel treatment target in psychiatry.

  title={Glutathione: a novel treatment target in psychiatry.},
  author={Michael Berk and Felicity Ng and Olivia M Dean and Seetal Dodd and Ashley I. Bush},
  journal={Trends in pharmacological sciences},
  volume={29 7},
There is accumulating evidence for oxidative stress mechanisms as common pathophysiological pathways in diverse psychiatric disorders, which offers novel treatment targets in oxidation biology systems. Of these the glutathione system has the most favourable theoretical foundation, given its dominance as the most generic of cellular antioxidants. Clinically, this hypothesis has been supported by several recently published studies that have reported on the efficacy of N-acetylcysteine, a… CONTINUE READING


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