Corpus ID: 18372772

Glutathione: Systemic Protectant Against Oxidative and Free Radical Damage

  title={Glutathione: Systemic Protectant Against Oxidative and Free Radical Damage},
  author={P. Kidd},
  • P. Kidd
  • Published 1997
  • Chemistry
  • The tripeptide thiol glutathione (GSH) has facile electron-donating capacity, linked to its sulfhydryl (—SH) group. Glutathione is an important water-phase antioxidant and essential cofactor for antioxidant enzymes; it provides protection also for the mitochondria against endogenous oxygen radicals. Its high electron-donating capacity combined with its high intracellular concentration endows GSH with great reducing power, which is used to regulate a complex thiol-exchange system (—SH —S-S… CONTINUE READING

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