Glutathione, glutathione-related enzymes, and oxidative stress in individuals with subacute occupational exposure to lead.

@article{Dobrakowski2016GlutathioneGE,
  title={Glutathione, glutathione-related enzymes, and oxidative stress in individuals with subacute occupational exposure to lead.},
  author={Michał Dobrakowski and Natalia Pawlas and Edyta Hudziec and Agnieszka Kozłowska and Agnieszka Mikołajczyk and Ewa Birkner and Sławomir Kasperczyk},
  journal={Environmental toxicology and pharmacology},
  year={2016},
  volume={45},
  pages={235-40}
}
The aim of the study was to investigate the influence of subacute exposure to lead on the glutathione-related antioxidant defense and oxidative stress parameters in 36 males occupationally exposed to lead for 40±3.2days. Blood lead level in the examined population increased significantly by 359% due to lead exposure. Simultaneously, erythrocyte glutathione level decreased by 16%, whereas the activity of glutathione-6-phosphate dehydrogenase in erythrocytes and leukocytes decreased by 28% and 10… CONTINUE READING