Glutaredoxin 1 mediates the protective effect of steady laminar flow on endothelial cells against oxidative stress-induced apoptosis via inhibiting Bim

@inproceedings{Li2017Glutaredoxin1M,
  title={Glutaredoxin 1 mediates the protective effect of steady laminar flow on endothelial cells against oxidative stress-induced apoptosis via inhibiting Bim},
  author={Yao Li and Meng Ren and Xiaoqun Wang and Xingxing Cui and Hongmei Zhao and Chuanrong Zhao and Jing Zhou and Yanan Guo and Yi Hu and Chen Yan and Bradford C. Berk and Jing Wang},
  booktitle={Scientific Reports},
  year={2017}
}
Endothelial cell apoptosis induced by oxidative stress is an early event in the development of atherosclerosis. Several antioxidant enzymes which can cope with oxidative stress are up-regulated by the anti-atherogenic laminar blood flow often seen in straight or unbranched regions of blood vessels. However, the molecular mechanism responsible for flow… CONTINUE READING