Glutaraldehyde-treated bovine pericardium: effects of lyophilization on cytotoxicity and residual aldehydes.

@article{Maizato2003GlutaraldehydetreatedBP,
  title={Glutaraldehyde-treated bovine pericardium: effects of lyophilization on cytotoxicity and residual aldehydes.},
  author={Marina Junko Shiotsu Maizato and Olga Zazuco Higa and M{\^o}nica Beatriz Mathor and Maria Aparecida Pires Camillo and Patric J Spencer and Ronaldo de Nogueira Moraes Pitombo and Cec{\'i}lia Am{\'e}lia de Carvalho Zavaglia and Adolfo A. Leirner},
  journal={Artificial organs},
  year={2003},
  volume={27 8},
  pages={692-4}
}
This work assesses the effect of lyophilization on the cytotoxicity and residual aldehyde concentration of glutaraldehyde-treated and lyophilized bovine pericardium (group A), comparing it to conventional glutaraldehyde-treated bovine pericardium (group B). Cytotoxicity was measured by incubating a pericardium sample from each group in saline and assessing the eluant's influence on cellular growth. Residual aldehydes were measured by HPLC. Although both groups' eluants exhibited some… CONTINUE READING

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