Glutaraldehyde-containing dentin bonding agents are mutagens in mammalian cells in vitro.

Abstract

The mutagenic potential of glutaraldehyde-containing dentin bonding agents was shown in previous studies using a bacterial gene mutation assay, the Ames test. However, current strategies of genotoxicity testing and regulatory requirements for the biological evaluation of medical devices recommend a battery of tests that indicate induced mutations in… (More)

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@article{Schweikl1997GlutaraldehydecontainingDB, title={Glutaraldehyde-containing dentin bonding agents are mutagens in mammalian cells in vitro.}, author={Helmut Schweikl and Gottifried Schmalz}, journal={Journal of biomedical materials research}, year={1997}, volume={36 3}, pages={284-8} }