Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal.

@article{Lee1998GlutamineTB,
  title={Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal.},
  author={W J Lee and Richard R. Hawkins and Juan Vina and Darryl R. Peterson},
  journal={American journal of physiology. Cell physiology},
  year={1998},
  volume={274 4},
  pages={C1101-C1107}
}
Glutamine and glutamate transport activities were measured in isolated luminal and abluminal plasma membrane vesicles derived from bovine brain endothelial cells. Facilitative systems for glutamine and glutamate were almost exclusively located in luminal-enriched membranes. The facilitative glutamine carrier was neither sensitive to 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid inhibition nor did it participate in accelerated amino acid exchange; it therefore appeared to be distinct from the… CONTINUE READING

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Neuroexcit - atory amino acids and their relation to infarct size and neurological deficit in ischemic

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