Glutamine is an important precursor for de novo synthesis of arginine in humans.

  title={Glutamine is an important precursor for de novo synthesis of arginine in humans.},
  author={Gerdien C Ligthart-Melis and Marcel C. G. van de Poll and Petra G. Boelens and Cornelis H. C. Dejong and Nicolaas E P Deutz and Paul A. M. van Leeuwen},
  journal={The American journal of clinical nutrition},
  volume={87 5},
BACKGROUND A metabolic relation exists between glutamine and arginine, 2 amino acids with properties that enhance the recovery of seriously ill patients. It is possible that glutamine exerts part of its beneficial effects by enhancing the availability of arginine. OBJECTIVES We aimed to quantify under postabsorptive conditions the metabolic pathway of plasma glutamine into arginine via the intermediate citrulline and to establish the contribution of the kidneys to the synthesis of arginine… CONTINUE READING
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