Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.

Abstract

PURPOSE Glutamine (GLN) is a precursor for synthesis of glutamate and gamma-aminobutyric acid (GABA) and has been found in the cerebrospinal fluid (CSF) at mean concentrations of 0.6 mM. Experiments on slices are usually performed in artificial CSF (aCSF) kept free of amino acids. Therefore, the role of glutamine, particularly in tissue of epileptic animals… (More)
DOI: 10.1111/j.1528-1167.2008.01973.x

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@article{Sandow2009GlutamineIE, title={Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.}, author={Nora Sandow and Robert Karl Zahn and Siegrun Gabriel and Uwe Heinemann and T. Lehmann}, journal={Epilepsia}, year={2009}, volume={50 4}, pages={849-58} }