Glutamine and fatty acid oxidation are the main sources of energy for Kupffer and endothelial cells.

@article{Spolarics1991GlutamineAF,
  title={Glutamine and fatty acid oxidation are the main sources of energy for Kupffer and endothelial cells.},
  author={Zolt{\'a}n Spolarics and Charles H Lang and Gregory J. Bagby and John J. Spitzer},
  journal={The American journal of physiology},
  year={1991},
  volume={261 2 Pt 1},
  pages={G185-90}
}
This study assessed and compared the rate of glucose utilization, activity of the hexose-monophosphate shunt (HMS), and the oxidation of glutamine, lactate, and palmitate in Kupffer (KC), endothelial (EC), and parenchymal liver cells (PC). Cells were isolated by collagenase and pronase digestion followed by centrifugal elutriation. The freshly isolated cells were incubated in the presence of 5 mM glucose, 0.5 mM glutamine, 1 mM lactate, and 0.4 mM palmitate, and the oxidation rate of individual… CONTINUE READING

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