Glutamine and barrier function in cultured Caco-2 epithelial cell monolayers.

@article{DeMarco2003GlutamineAB,
  title={Glutamine and barrier function in cultured Caco-2 epithelial cell monolayers.},
  author={Vincent G DeMarco and Nan Li and Justin Thomas and Christopher M. West and Josef Neu},
  journal={The Journal of nutrition},
  year={2003},
  volume={133 7},
  pages={2176-9}
}
Dietary glutamine (Gln) has been shown to be important for maintenance of the intestinal barrier. To investigate the role of the epithelium in this Gln dependence, Caco-2 cells were raised on semipermeable membranes under conditions that model different regions of the crypt and villus. Gln availability was controlled by addition to the medium and treatment… CONTINUE READING