Glutamine and arginine affect Caco-2 cell proliferation by promotion of nucleotide synthesis.

@article{Yamauchi2002GlutamineAA,
  title={Glutamine and arginine affect Caco-2 cell proliferation by promotion of nucleotide synthesis.},
  author={Keiko Yamauchi and Tatsushi Komatsu and Anil D. Kulkarni and Yoshinobu Ohmori and Hisanori Minami and Yuh Ushiyama and Mitsuo Nakayama and Shigeru Yamamoto},
  journal={Nutrition},
  year={2002},
  volume={18 4},
  pages={329-33}
}
OBJECTIVE We tested our hypothesis that 1) the major effect of Gln is as a nitrogen donor, not an energy source, for nucleotides (NT) and 2) the supplementation of culture medium with arginine (Arg) decreases the flux of glutamine (Gln) for conversion to Arg, thus accelerating NT synthesis. METHODS Various concentrations of nucleosides (NS+NT) Gln, and… CONTINUE READING