Glutamine and Whey Protein Improve Intestinal Permeability and Morphology in Patients with Crohn’s Disease: A Randomized Controlled Trial

@article{Benjamin2011GlutamineAW,
  title={Glutamine and Whey Protein Improve Intestinal Permeability and Morphology in Patients with Crohn’s Disease: A Randomized Controlled Trial},
  author={Jaya Benjamin and Govind Kumar Makharia and Vineet Ahuja and K. D. Anand Rajan and M. S. Kalaivani and Siddhartha Datta Gupta and Y. Joshi},
  journal={Digestive Diseases and Sciences},
  year={2011},
  volume={57},
  pages={1000-1012}
}
Increased intestinal permeability (IP) has been implicated in the etiopathogenesis, disease activity and relapse of Crohn’s disease (CD). Glutamine, the major fuel for the enterocytes, may improve IP. We evaluated the effect of oral glutamine on IP and intestinal morphology in patients with CD. In a randomized controlled trial, consecutive patients with CD in remission phase with an abnormal IP were randomized to a glutamine group (GG) or active control group (ACG) and were given oral glutamine… CONTINUE READING
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