Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP

@inproceedings{Tolhurst2011GlutamineTA,
  title={Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP},
  author={Gwen Tolhurst and Yue Zheng and Helen E. Parker and Abdella M. Habib and F Reimann and Fiona Mary Gribble},
  booktitle={Endocrinology},
  year={2011}
}
L-glutamine stimulates glucagon-like peptide 1 (GLP-1) secretion in human subjects and cell lines. As recent advances have enabled the study of primary GLP-1-releasing L cells, this study aimed to characterize glutamine-sensing pathways in native murine L cells. L cells were identified using transgenic mice with cell-specific expression of fluorescent… CONTINUE READING