Glutamine: A novel approach to chemotherapy-induced toxicity

@article{Gaurav2012GlutamineAN,
  title={Glutamine: A novel approach to chemotherapy-induced toxicity},
  author={Kumar Gaurav and Ruchi Goel and Mridula Shukla and Manoj Pandey},
  journal={Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical \& Paediatric Oncology},
  year={2012},
  volume={33},
  pages={13 - 20}
}
  • K. Gaurav, R. Goel, +1 author M. Pandey
  • Published 2012
  • Medicine
  • Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology
Treatment of cancer is associated with short- and long-term side-effects. Cancer produces a state of glutamine deficiency, which is further aggravated by toxic effects of chemotherapeutic agents leading to increased tolerance of tumor to chemotherapy as well as reduced tolerance of normal tissues to the side-effects of chemotherapy. This article reviews the possible role of glutamine supplementation in reducing the serious adverse events in patients treated with anticancer drugs. The literature… Expand
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