Glutamatergic synapses in neurodevelopmental disorders

@article{Moretto2017GlutamatergicSI,
  title={Glutamatergic synapses in neurodevelopmental disorders},
  author={Edoardo Moretto and Luca Murru and Giuseppe Martano and Jenny Sassone and Maria Passafaro},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2017},
  volume={84},
  pages={328-342}
}
Neurodevelopmental disorders (NDDs) are a group of diseases whose symptoms arise during childhood or adolescence and that impact several higher cognitive functions such as learning, sociability and mood. Accruing evidence suggests that a shared pathogenic mechanism underlying these diseases is the dysfunction of glutamatergic synapses. We summarize present knowledge on autism spectrum disorders (ASD), intellectual disability (ID), Down syndrome (DS), Rett syndrome (RS) and attention-deficit… CONTINUE READING

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