Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control.

@article{Talman1984GlutamatergicMI,
  title={Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control.},
  author={William T Talman and Antonio Raffaele Michele Granata and Donald J. Reis},
  journal={Federation proceedings},
  year={1984},
  volume={43 1},
  pages={39-44}
}
The nucleus tractus solitarius (NTS), the site of termination of visceral afferents of the ninth and tenth cranial nerves, mediates and integrates the reflex cardiovascular and noncardiovascular responses to stimulation of cardiopulmonary and other visceral afferents. On injection into the NTS, the amino acid L-glutamate (L-Glu) and its excitatory analogs produce dose-dependent hypotension and bradycardia, a baroreceptor reflex-like response. The L-Glu antagonist glutamate diethyl ester blocks… CONTINUE READING