Glutamatergic inhibition in sensory neocortex.

  title={Glutamatergic inhibition in sensory neocortex.},
  author={Charles C. Lee and S. Murray Sherman},
  journal={Cerebral cortex},
  volume={19 10},
In the mammalian brain, glutamate and gamma-aminobutyric acid are considered major excitatory and inhibitory neurotransmitters, respectively. However, we have found evidence that glutamate can also act as a postsynaptic inhibitory neurotransmitter in layer 4 of the neocortex. Using whole-cell recordings from layer 4 neurons in slice preparations from the mouse visual, auditory, and somatosensory cortices, we found that metabotropic glutamate receptor (mGluR) agonists (ACPD, APDC, and DCG IV… CONTINUE READING
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Photorelease of carboxylic acids from 1-acyl-7-nitroindolines in aqueous solution: rapid and efficient photorelease of L-glutamate

  • G Papageorgiou, DC Ogden, A Barth, JET. Corrie
  • J Am Chem Soc. 121:6503--6504.
  • 1999
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