Glutamate transport and metabolism in astrocytes.

@article{Sonnewald1997GlutamateTA,
  title={Glutamate transport and metabolism in astrocytes.},
  author={U. Sonnewald and N. Westergaard and A. Schousboe},
  journal={Glia},
  year={1997},
  volume={21 1},
  pages={
          56-63
        }
}
Glutamate uptake and metabolism was studied in cerebral cortical astrocytes. The expression of the astrocytic glutamate transporter GLAST was found to be stimulated by extracellular glutamate through activation of kainate receptors on the astrocytes. Energy metabolism and ammonia homeostasis are two important aspects of glutamate handling in astrocytes. It is well known that glutamate transport into astrocytes and glutamine formation are energy consuming processes. Furthermore, ammonia is… Expand
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