Glutamate receptor ion channels.

  title={Glutamate receptor ion channels.},
  author={Mark L Mayer},
  journal={Current opinion in neurobiology},
  volume={15 3},
  • Mark L Mayer
  • Published 2005 in Current opinion in neurobiology
Glutamate receptor ion channels mediate excitatory responses at the majority of CNS synapses. They are the only ligand-gated ion channels for which multiple high-resolution crystal structures have been solved. Highlights of information gained from mechanistic studies based on the crystal structures of their ligand-binding domains include explanations for strikingly diverse phenomena. These include the basis for subtype-specific agonist selectivity; mechanisms for desensitization and allosteric… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 86 extracted citations

Similar Papers

Loading similar papers…