Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

@article{Setou2002GlutamatereceptorinteractingPG,
  title={Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites},
  author={Mitsutoshi Setou and D H Seog and Yosuke Tanaka and Yoshimitsu Kanai and Yosuke Takei and Masahiko Kawagishi and Nobutaka Hirokawa},
  journal={Nature},
  year={2002},
  volume={417},
  pages={83-87}
}
In cells, molecular motors operate in polarized sorting of molecules, although the steering mechanisms of motors remain elusive. In neurons, the kinesin motor conducts vesicular transport such as the transport of synaptic vesicle components to axons and of neurotransmitter receptors to dendrites, indicating that vesicles may have to drive the motor for the… CONTINUE READING