Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation.

Abstract

Glutamate loading has been shown to protect single isolated perfused cardiomyocytes against metabolic inhibition and wash-off. The mechanism underpinning this protection is unknown. This study aimed to investigate whether reactive oxygen species (ROS) are generated by single isolated perfused cardiomyocytes and whether the protective effect of glutamate… (More)

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