Glutamate-dopamine interactions mediate the effects of psychostimulant drugs.

Abstract

The striatum, a major central nervous system structure modulating movement, is enriched with glutamatergic and dopaminergic innervation. By altering activities of both glutamatergic and dopaminergic transmissions the psychostimulants, amphetamine and cocaine, induce behavioral changes in experimental animals. Activation of the two systems is also essential… (More)
DOI: 10.1080/13556219971641

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