Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves.

@article{Dodd1992GlutamateAG,
  title={Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves.},
  author={Peter Ronald Dodd and Stephen H. Williams and Andrew L Gundlach and Patricia A. Harper and Peter J. Healy and Julie A. Dennis and Graham A. R. Johnston},
  journal={Journal of neurochemistry},
  year={1992},
  volume={59 2},
  pages={
          582-90
        }
}
Cerebral cortex tissue was obtained at autopsy from neonatal Poll Hereford calves with clinically confirmed maple syrup urine disease (MSUD), neonatal Holstein-Friesian calves with clinically confirmed citrullinemia, and matched controls. From this, synaptosomes were prepared for studies of neurotransmitter amino acid uptake and stimulus-induced release, and synaptic plasma membranes were obtained for studies of associated postsynaptic receptor binding sites. As well as having abnormal brain… CONTINUE READING
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