Glutamate and aspartate activated channels and inhibitory synaptic currents in large cerebellar neurons grown in culture.

@article{CullCandy1987GlutamateAA,
  title={Glutamate and aspartate activated channels and inhibitory synaptic currents in large cerebellar neurons grown in culture.},
  author={Stuart G Cull-Candy and Maria M. Usowicz},
  journal={Brain research},
  year={1987},
  volume={402 1},
  pages={182-7}
}
Patch-clamp methods were used to examine large (greater than 30 microns) cerebellar neurons of the rat, maintained in cell culture. Cells possessed voltage-activated transient inward Na+ currents which were sensitive to tetrodotoxin. Spontaneous synaptic currents, present in whole-cell recordings, were abolished by bicuculline and picrotoxin and were carried by Cl-. Cells produced inward currents in response to the transmitter candidates glutamate and aspartate and also to the glutamate… CONTINUE READING