Glue-sniffing and distal renal tubular acidosis: sticking to the facts.

@article{Carlisle1991GluesniffingAD,
  title={Glue-sniffing and distal renal tubular acidosis: sticking to the facts.},
  author={Euan J. F. Carlisle and Sandra M. Donnelly and Somkiat Vasuvattakul and Kamel S Kamel and Sheldon W Tobe and Mitchell L. Halperin},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1991},
  volume={1 8},
  pages={1019-27}
}
An index case is presented to introduce the subject of the acid-base and electrolyte abnormalities resulting from toluene abuse. These include metabolic acidosis associated with a normal anion gap and excessive loss of sodium and potassium in the urine. The major question addressed is, what is the basis for the metabolic acidosis? Overproduction of hippuric acid resulting from the metabolism of toluene plays a more important role in the genesis of the metabolic acidosis than was previously… CONTINUE READING
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