Glucuronidation of bile acids in human liver, intestine and kidney. An in vitro study on hyodeoxycholic acid.

Abstract

The activities of UDP-glucuronyl transferase(s) in homogenates and microsomal preparations of human liver, kidney and intestine were tested with hyodeoxycholic acid (HDC). The various kinetic parameters of the UDC-glucuronidation were determined from time course experiments. In both liver and kidney preparations, HDC underwent a very active metabolic… (More)

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