Glucose stimulation of insulin secretion in islets of fed and starved rats and its dependence on lipid metabolism.

@article{Vara1986GlucoseSO,
  title={Glucose stimulation of insulin secretion in islets of fed and starved rats and its dependence on lipid metabolism.},
  author={Elena Vara and Jorge Tamarit-Rodriguez},
  journal={Metabolism: clinical and experimental},
  year={1986},
  volume={35 3},
  pages={266-71}
}
The influence of a physiologic range of palmitate concentrations (0, 0.25, 0.5, and 1.0 mmol/L) on glucose ability to modify insulin secretion, (U-14C) palmitate oxidation, and (U-14C) glucose incorporation into lipids has been studied in islets isolated from either fed or 48-hour starved rats. Palmitate potentiated the insulin response of fed islets to glucose in a particular dose-related manner. Glucose stimulated secretion was accompanied by a decreased palmitate oxidation and an increased… CONTINUE READING

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