Glucose sensing through the Hxk2-dependent signalling pathway.

@article{Moreno2005GlucoseST,
  title={Glucose sensing through the Hxk2-dependent signalling pathway.},
  author={Florencio Moreno and Deifilia Ahuatzi and Alberto Riera and Carlos A. Palomino and Pilar Herrero},
  journal={Biochemical Society transactions},
  year={2005},
  volume={33 Pt 1},
  pages={
          265-8
        }
}
In this work, we describe the hexokinase 2 (Hxk2) signalling pathway within the yeast cell. Hxk2 and Mig1 are the two major factors of glucose repression in Saccharomyces cerevisiae. The functions of both proteins have been extensively studied but there is no information about possible interactions among them in the repression pathway. Our results demonstrate that Hxk2 interacts directly with Mig1 in vivo and in vitro and that the ten amino acids motif between K6 and M15 is required for their… CONTINUE READING

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