Glucose-sensing neurons: are they physiologically relevant?

  title={Glucose-sensing neurons: are they physiologically relevant?},
  author={Vanessa H. Routh},
  journal={Physiology & behavior},
  volume={76 3},
Glucose homeostasis is of paramount concern to the brain since glucose is its primary fuel. Thus, the brain has evolved mechanisms to sense and respond to changes in glucose levels. The efferent aspects of the central nervous system response to hypoglycemia are relatively well understood. In addition, it is accepted that the brain regulates food intake and energy balance. Obesity and diabetes both result from and cause alterations in the central nervous system function. Thus, it is reasonable… CONTINUE READING
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Defective ATP and sulfonylurea sensitivity of the ATP-sensitive K (KATP) channel in the ventromedial hypothalamic nucleus (VMN) of obesity-prone (DIO) rats

  • VH Routh, BE Levin, JJ. McArdle
  • FASEB J 2001;12:A864
  • 2001
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