Glucose regulation of gene expression.

  title={Glucose regulation of gene expression.},
  author={Fabienne Foufelle and Jean Girard and Pascal Ferr{\'e}},
  journal={Current opinion in clinical nutrition and metabolic care},
  volume={1 4},
Regulation of gene expression by nutrients in mammals is an important mechanism allowing them to adapt to the nutritional environment. In-vivo and in-vitro experiments have demonstrated that the transcription of genes coding for lipogenic and glycolytic enzymes in liver and/or adipose tissue is upregulated by glucose. In order for glucose to act as a gene inducer, it must be metabolized. Recent evidence suggests that glucose-6-phosphate is the signal metabolite in the liver. DNA glucose… CONTINUE READING
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