Glucose metabolism and insulin receptor binding and mRNA levels in tissues of Dahl hypertensive rats.

@article{Sechi1997GlucoseMA,
  title={Glucose metabolism and insulin receptor binding and mRNA levels in tissues of Dahl hypertensive rats.},
  author={Leonardo A Sechi and Cora A Griffin and Laura Zingaro and Cristiana Catena and Stefano de Carli and Morris Schambelan and Ettore Bartoli},
  journal={American journal of hypertension},
  year={1997},
  volume={10 11},
  pages={1223-30}
}
Increased insulinemic response to an oral glucose load has been demonstrated in Dahl salt-sensitive hypertensive rats. To determine whether this abnormality is mediated at the level of the insulin receptor, we compared insulin receptor binding and mRNA levels in tissues of Dahl salt-sensitive rats (DS) and in their normotensive controls, Dahl salt-resistant rats (DR). To evaluate possible influences of dietary sodium intake, rats were fed either low (0.07% NaCl) or high salt (7.5% NaCl) chow… CONTINUE READING