Glucose-mediated transcriptional repression of PCB/biphenyl catabolic genes in Rhodococcus jostii RHA1.

@article{Araki2011GlucosemediatedTR,
  title={Glucose-mediated transcriptional repression of PCB/biphenyl catabolic genes in Rhodococcus jostii RHA1.},
  author={N. Araki and Yuji Niikura and Keisuke Miyauchi and Daisuke Kasai and Eiji Masai and Masao Fukuda},
  journal={Journal of molecular microbiology and biotechnology},
  year={2011},
  volume={20 1},
  pages={53-62}
}
Rhodococcus jostii RHA1, a Gram-positive polychlorinated biphenyl (PCB) degrader, exhibited biphasic growth in a medium containing biphenyl (BPH) and glucose (Glc), with consumption of Glc and low 2,3-dihydroxybiphenyl 1,2-dioxygenase activity in the first growth stage. These results suggested the repression of BPH metabolism in the presence of Glc, in which RHA1 preferentially utilized Glc in the first growth stage and BPH in the second stage. A reporter assay using a transcriptional fusion of… CONTINUE READING