Glucose is a key metabolic regulator of osteoclasts; glucose stimulated increases in ATP/ADP ratio and calmodulin kinase II activity.

@article{Larsen2005GlucoseIA,
  title={Glucose is a key metabolic regulator of osteoclasts; glucose stimulated increases in ATP/ADP ratio and calmodulin kinase II activity.},
  author={Kirsten I Larsen and Marina L Falany and Wei Wang and John Michael Williams},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2005},
  volume={83 5},
  pages={667-73}
}
Glucose-stimulated increases in osteoclast activity are mediated, at least in part, by transcriptional regulation of H+-ATPase expression through a mechanism involving p38 mitogen-activated protein kinase. We hypothesized that early events in the glucose-dependent signaling pathway would be similar to those identified in other glucose-sensitive cells, such… CONTINUE READING