Glucose injection reduces neuropeptide Y and agouti-related protein expression in the arcuate nucleus: a possible physiological role in eating behavior.

@article{Chang2005GlucoseIR,
  title={Glucose injection reduces neuropeptide Y and agouti-related protein expression in the arcuate nucleus: a possible physiological role in eating behavior.},
  author={Guo-qing Chang and Olga Karatayev and Zoya Davydova and Katherine E. Wortley and Sarah Fryer Leibowitz},
  journal={Brain research. Molecular brain research},
  year={2005},
  volume={135 1-2},
  pages={
          69-80
        }
}
Evidence suggests that neuropeptide Y (NPY) and agouti-related protein (AgRP) in the arcuate nucleus (ARC) are modulated by glucoregulatory hormones and involved in maintaining normal eating patterns and glucose homeostasis in states of energy deficiency. This study investigated whether these peptides respond to glucose itself under conditions, e.g., before the nocturnal feeding cycle, when carbohydrate stores are low. After removal of food 3 h before dark onset, Sprague-Dawley rats were given… CONTINUE READING
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