Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway.

  title={Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway.},
  author={Jose F{\'e}lix Moruno-Manch{\'o}n and Eva P{\'e}rez-Jim{\'e}nez and Erwin Knecht},
  journal={The Biochemical journal},
  volume={449 2},
Autophagy is a natural process of 'self-eating' that occurs within cells and can be either pro-survival or can cause cell death. As a pro-survival mechanism, autophagy obtains energy by recycling cellular components such as macromolecules or organelles. In response to nutrient deprivation, e.g. depletion of amino acids or serum, autophagy is induced and most of these signals converge on the kinase mTOR (mammalian target of rapamycin). It is commonly accepted that glucose inhibits autophagy… CONTINUE READING
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for three independent experiments with respect to KH medium without glucose. ***P < 0.005

  • S.D
  • Glc, glucose. Received
  • 2012

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