Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations.

@article{Vaag1994GlucosefattyAC,
  title={Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations.},
  author={Allan A. Vaag and Aase Handberg and P. Sk{\o}tt and Erik Arne Richter and Henning Beck-Nielsen},
  journal={European journal of endocrinology},
  year={1994},
  volume={130 1},
  pages={
          70-9
        }
}
Plasma non-esterified fatty acid concentrations were elevated acutely (Intralipid+heparin infusion) in 14 normal humans in order to study the effects of fatty acids on whole-body basal and insulin-stimulated glucose metabolism, and on activities of skeletal muscle key enzymes. Whole-body glucose metabolism was assessed using [3-3H]glucose and indirect calorimetry. Biopsies were taken from the vastus lateralis muscle during basal and insulin-stimulated (3 h, 40 mU.m-2.min-1) steady-state periods… Expand
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