Glucose deprivation depolarizes plasma membrane of cultured astrocytes and collapses transmembrane potassium and glutamate gradients.

@article{Kauppinen1988GlucoseDD,
  title={Glucose deprivation depolarizes plasma membrane of cultured astrocytes and collapses transmembrane potassium and glutamate gradients.},
  author={Risto A. Kauppinen and K Enkvist and Ilkka Holopainen and Karl E Akerman},
  journal={Neuroscience},
  year={1988},
  volume={26 1},
  pages={283-9}
}
Primary cultures of astrocytes were used to investigate the effects of glucose deprivation on plasma membrane potential, on the respiration and on the energy status of these cells. Plasma membrane potential, as monitored with a cyanine dye, 3,3'-diethylthiadicarbocyanine, hyperpolarized by about 100% when glucose was added to substrate-deprived cells. The… CONTINUE READING