Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth.

@article{Buhren2009GlucosedependentIP,
  title={Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth.},
  author={Bettina Alexandra Buhren and Marcia Gasis and Bernard Thorens and Hans Werner M{\"u}ller and Frank Bosse},
  journal={Journal of neuroscience research},
  year={2009},
  volume={87 8},
  pages={1858-70}
}
Glucose-dependent insulinotropic polypeptide (GIP) was initially described to be rapidly regulated by endocrine cells in response to nutrient ingestion, with stimulatory effects on insulin synthesis and release. Previously, we demonstrated a significant up-regulation of GIP mRNA in the rat subiculum after fornix injury. To gain more insight into the lesion-induced expression of GIP and its receptor (GIPR), expression profiles of the mRNAs were studied after rat sciatic nerve crush injury in 1… CONTINUE READING