Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes.

@article{Teta2005GlucosecontainingPD,
  title={Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes.},
  author={D. Teta and Andr{\'e}e Tedjani and M. Burnier and A. Bevington and J. Brown and K. Harris},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2005},
  volume={20 7},
  pages={
          1329-35
        }
}
  • D. Teta, Andrée Tedjani, +3 authors K. Harris
  • Published 2005
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • BACKGROUND A marked elevation of serum leptin is observed soon after the start of peritoneal dialysis (PD), suggesting that leptin production may be stimulated by this treatment. Glucose metabolism is the major factor regulating leptin. The current study was designed to test if glucose-based PD fluids might regulate leptin production in vitro. METHODS 3T3-L1 adipocytes were exposed to a 50:50 mixture of dialysis solutions and medium M199 containing 10% serum for <or=48 h. Leptin secretion in… CONTINUE READING
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