Glucose and cholesterol elevations during thiazide therapy: intention-to-treat versus actual on-therapy experience.

@article{Elliott1995GlucoseAC,
  title={Glucose and cholesterol elevations during thiazide therapy: intention-to-treat versus actual on-therapy experience.},
  author={William J. Elliott},
  journal={The American journal of medicine},
  year={1995},
  volume={99 3},
  pages={261-9}
}
PURPOSE This nonrandomized, parallel-group, prospective clinical series in consecutive patients was conducted to determine if the method of analysis of biochemical data collected in long-term treatment trials can explain the controversy regarding the effects of thiazides on plasma glucose or cholesterol. PATIENTS AND METHODS Fasting serum glucose, potassium, and cholesterol levels were determined before therapy, and yearly thereafter (4.0 +/- 0.1 years) in 634 consecutive patients treated for… CONTINUE READING