Glucose Repression of Amylase Gene Expression in DROSOPHILA MELANOGASTER.

  title={Glucose Repression of Amylase Gene Expression in DROSOPHILA MELANOGASTER.},
  author={Bernhard F. Benkel and Donal A. Hickey},
  volume={114 1},
We have previously shown that dietary glucose can reduce amylase activity in both adults and larvae of Drosophila; this reduction in enzyme activity reflects a reduction in the quantity of amylase protein, rather than an inhibition of enzyme activity. Here, we report that we have now defined conditions in which the repressive effect of glucose can be greater than 100-fold. Moreover, this repression is partially counteracted by the addition of exogenous cyclic AMP. We also show that there is a… CONTINUE READING

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