Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

@inproceedings{Palmer2015GlucoseMR,
  title={Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions},
  author={Clovis S Palmer and Matias Ostrowski and Brad Balderson and Nicole A Christian and Suzanne M. Crowe},
  booktitle={Front. Immunol.},
  year={2015}
}
The adaptive immune system is equipped to eliminate both tumors and pathogenic microorganisms. It requires a series of complex and coordinated signals to drive the activation, proliferation, and differentiation of appropriate T cell subsets. It is now established that changes in cellular activation are coupled to profound changes in cellular metabolism. In addition, emerging evidence now suggest that specific metabolic alterations associated with distinct T cell subsets may be ancillary to… CONTINUE READING
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Posttranscriptional control of T cell effector function by aerobic glycolysis

  • CH Chang, JD Curtis, LB Jr.Maggi, B Faubert, AV Villarino, D O’Sullivan
  • Cell
  • 2013
Highly Influential
8 Excerpts

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

  • GM Delgoffe, KN Pollizzi, AT Waickman, E Heikamp, DJ Meyers, MR Horton
  • Nat Immunol
  • 2011
Highly Influential
3 Excerpts

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