Glucose Homeostasis in the Teleost Fish Tilapia : Insights from Brockmann Body Xenotransplantation Studies

@inproceedings{Bonen2000GlucoseHI,
  title={Glucose Homeostasis in the Teleost Fish Tilapia : Insights from Brockmann Body Xenotransplantation Studies},
  author={Arend Bonen and J Michael Conlon and Bill Pohajdak},
  year={2000}
}
SYNOPSIS. Certain teleost fish have large anatomically discrete islet organs called Brockmann bodies (BBs). When transplanted into streptozotocin diabetic athymic nude mice, tilapia BBs provide long-term normoglycemia. This has afforded us the opportunity to examine tilapia islet in vivo function in a non-piscine environment and compare this with in vivo function in the donor species. As expected, fasting and non-fasting glycemic levels in long-term murine recipients of tilapia BBs were… CONTINUE READING
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