Glucose-6-phosphate dehydrogenase deficiency and malaria: cytochemical detection of heterozygous G6PD deficiency in women.

@article{Peters2009Glucose6phosphateDD,
  title={Glucose-6-phosphate dehydrogenase deficiency and malaria: cytochemical detection of heterozygous G6PD deficiency in women.},
  author={Anna L Peters and Cornelis J. F. van Noorden},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2009},
  volume={57 11},
  pages={1003-11}
}
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a X-chromosomally transmitted disorder of the erythrocyte that affects 400 million people worldwide. Diagnosis of heterozygously-deficient women is complicated: as a result of lyonization, these women have a normal and a G6PD-deficient population of erythrocytes. The cytochemical assay is the only reliable assay to discriminate between heterozygously-deficient women and non-deficient women or homozygously-deficient women. G6PD deficiency is… CONTINUE READING
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